You can instantiate a plug-in on any kind of track (audio, software instrument, aux, or master) or grouped tracks in Logic Pro. In the following steps, we'll use AmpliTube 5 as an example, and instantiate it on an audio track.

1. Click on the track name of the track you want to instantiate the plug-in on so the track is displayed in the Left inspector channel strip.
2. Click in the Audio FX section of the track in the Left inspector channel strip.
3. Select Audio Units, find the plug-in in the appropriate folder, then click either Mono→Stereo (advised if the plug-in utilizes stereo effects) or Mono. For AmpliTube 5, click Audio Units > IK Multimedia > Amplitube 5 > Mono→Stereo.